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Dr. Knight carried on a family tradition, as both his father and grandfather were physicians. At the tender age of eight he decided upon medicine as a career and never regretted the decision. Following the receipt of an AB degree from Dartmouth College in 1926, he obtained his MD from P & S Columbia in 1930 and interned at both Presbyterian and Bellevue Hospital in New York.
Upon entering private practice in Westchester County, NY, Dr. Knight soon realized that something was wrong with routine ear, nose and throat treatment. Deciding that allergy was a significant factor in unsatisfactory treatment results, he took postgraduate courses and attended clinics in this subject. As a result, much of his practice and treatments focused on addressing allergies. It was not long before he realized that good nutrition was fundamental to the healing arts and this was a part of his approach to all medical problems for most of his career.
Dr. Knight was on the staff of the Cottage, St. Francis and County General Hospitals in Santa Barbara as well as being a Consultant in Allergy to Our Lady of Perpetual Help Hospital in Santa Maria. He was active in many medical societies including the California Allergy Society, Los Angeles Society of Allergy and the International Correspondence Society of Allergists. He was a fellow of the American Academy of Ophthalmology and Otolaryngology, the American College of Allergists and the International Society of Allergists and the International Society of Allergists (Founders Group).
In 1967 Dr. Knight became the founding President of the Weston A. Price Memorial Foundation (now the Price-Pottenger Nutrition Foundation). He served in that position for 17 years.
Dr. Knight wrote many papers on allergies, chemical pesticides, chemical pollution, and fluoridation hazards and was a frequent witness in court trials across the United States as an expert of the dangers of mass chemical pesticide use.