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Two coastal areas in Nova Scotia have an extraordinary number of centenarians [50 per 100,000 population]. Why is it they are not predisposed to chronic disease like people in the United States? Medical scientists have taken on the task of explaining the nearly threefold advantage held by these Nova Scotians. "Scientists suspect there may be a few age-defying genes and hope to develop drugs that mimic their action." The medical scientists chasing hypothetical age-defying genes, so as to produce and peddle magic bullets, blithely forget that our metabolic enzyme systems require nutrients from the external environment in order to carry out the genetic instructions for regulation of our internal environment.