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New research published in the journal Nutrients found that tocotrienol-rich vitamin E improved kidney function parameters in patients with diabetic kidney disease, a complication of diabetes that can result in end-stage renal failure.
In the double-blind, placebo-controlled trial, people in the test group were given 200 mg of tocotrienol- rich vitamin E twice daily for a year. After eight months, those receiving vitamin E showed improvements in renal function as indicated by reduced serum creatine levels and increased estimated glomerular filtration rates. No significant changes were observed in other markers related to kidney function, such as urea, uric acid, or glycated hemoglobin (HBA1c).
Vitamin E tocotrienols have certain properties that the more commonly used tocopherols lack. Based on previous research, tocotrienols may be beneficial in treating a range of health conditions, including certain cancers, metabolic syndrome, type 2 diabetes, non-alcoholic fatty liver disease, and age-related eye disorders.
This new study is the first to demonstrate that tocotrienol-rich vitamin E supplementation may improve renal function and potentially reduce the progression of diabetic kidney disease, particularly in patients with stage 3 (moderate) chronic kidney disease.
Sources: Higgins C. Recent study indicates supplementation of tocotrienol-rich vitamin E supports kidney function. Designs for Health, March 4, 2021. blog.designsforhealth.com/node/1373.
Koay YY, Tan G, Phang S, et al. A phase IIb randomized controlled trial investigating the effects of tocotrienol- rich vitamin E on diabetic kidney disease. Nutrients. 2021; 13(1):258. doi.org/10.3390/nu13010258.
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Published in the Price-Pottenger Journal of Health and Healing
Spring 2021 | Volume 45, Number 1
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